For patients with chronic viral hepatitis B, there are two reasons for itchy skin. The first reason is the deposition of bile salts, which causes itchy skin. The other reason is that the patient’s bilirubin is too high, causing hyperbilirubinemia, resulting in the patient’s skin sclera yellowing after the corresponding skin itching. In this case, it is mostly considered that the patient has liver dysfunction, liver cell necrosis, and the possibility of hepatocellular jaundice occurs. At this time, it is recommended that the patient should firstly take blood tests to check the blood routine, liver function and ultrasound of the upper abdomen. If the patient’s liver function is impaired, glutamic acid and glutamic oxal transaminase are elevated, and the patient has liver fibrosis and cirrhosis, the patient should consider further antiviral treatment. Patients should actively consider further antiviral treatment, as well as the need to carry out the gateway to cut off the flow of surgical treatment. In addition, patients should take a variety of micronutrients and vitamin C, pay attention to rest, do not drink alcohol, do not stay up all night.