Invasive gastric cancer requires surgical treatment because surgery is its main treatment modality. Currently, gastrectomy is the most widely used method to treat invasive gastric cancer, total gastrectomy is usually used to treat lesions in the proximal part of the stomach, while partial gastrectomy with adjacent lymph node dissection is enough to treat lesions in the distal part of the stomach, and it is important to note that patients with large lesions in the middle part of the stomach or infiltrative lesions may also need total gastrectomy. However, if invasive gastric cancer is found to have distant metastasis, such as lymph node metastasis, and the degree of infiltration is deeper, then the chance of surgery is smaller, and only conservative treatments, such as chemotherapy and radiotherapy, can be used to slow down the progression of the disease and prolong the survival period. It is recommended that once diagnosed with invasive gastric cancer, one should seek medical treatment in time and standardize treatment under professional doctor’s guidance, so as to avoid delaying the condition.