Periorbital pain has many causes, which may be caused by physiological factors, but may also be caused by pathological factors, such as dry eye, eye infection, eye trauma, etc. Patients should consult the doctor in time to find out the causes. 1. Physiological factors: If patients use their eyes excessively for a long time or do not have enough sleep, it will cause periorbital pain, which may be accompanied by dry eyes, pain and other uncomfortable symptoms. 2. Pathologic factors (1) Dry eye disease: dry eye disease patients because of insufficient tear secretion or evaporation of the eye surface dry, dry eyes, fatigue, soreness, eye pain and other discomfort symptoms. (2) Eye infection: If patients often rub their eyes with unclean hands, it will cause some bacteria or germs to invade into the eyes, resulting in eye infection, under the stimulation of inflammation, patients may experience discomfort symptoms such as swelling and pain around the eyes. (3) Ocular trauma: patients with ocular trauma may experience orbital pain due to mechanical stimulation, as well as subcutaneous bruising and other uncomfortable symptoms. It is recommended that patients with significant periorbital pain should consult a doctor to evaluate their condition and follow the doctor’s instructions for treatment.