Middle-aged women with pain in the middle of the two breasts may be caused by sternitis, intercostal neuralgia, costochondritis, trauma, etc. Some anti-inflammatory and pain-relieving medications can be taken to help relieve the pain. 1. Sternitis: Sternitis can cause a tingling sensation at the sternum (i.e., in the middle of the two breasts). The affected sternum is usually accompanied by slight or obvious redness and swelling, and accompanied by clear pressure pain, you can take oral nimesulide capsules, ibuprofen extended-release capsules and other drugs to relieve pain. 2. Intercostal neuralgia: Intercostal neuralgia can also occur in the middle of the breasts, the patient is prone to chest pain, usually mainly manifested as tingling or burning pain. Aspirin, indomethacin, ibuprofen and other drugs can be taken to relieve pain. 3. Costochondritis: Costochondritis is usually more obvious symptoms of pain during breathing and movement, and there is more obvious pain when pressed. Usually naproxen, prednisone, ibuprofen and other drugs can be used to help relieve pain. 4. Trauma: If trauma causes soft tissue contusion can also cause pain, such as car accidents or impact caused by soft tissue contusion can cause pain. When the pain is severe, you need to go to the hospital to check whether the bone is injured. Soft tissue contusion can be treated with drugs such as Diosmin, Indomethacin and Ibuprofen. If middle-aged women experience long-term or recurring pain in the middle of both breasts, it is recommended that they go to the hospital in a timely manner to find out the cause of the pain and be treated under the guidance of a doctor. If you need to use drugs, be sure to use them under the guidance of a professional doctor, to avoid improper use of medication to cause harm to the body or delay the condition.