Pancreatic exocrine insufficiency needs to be diagnosed according to the symptoms as well as the examination; causing pancreatic insufficiency is usually related to the reduction of digestive enzymes, chronic pancreatitis and other factors, which can be treated conservatively or surgically according to the cause. 1. Diagnosis of pancreatic exocrine insufficiency: (1) Symptoms: people with pancreatic exocrine insufficiency may often experience weakness, nausea, vomiting, loss of appetite, anorexia, etc. Some patients may have symptoms such as weight loss and diarrhea. (2) Related examination: mainly through the test of cholecystokinin, or fecal chymotrypsin and fecal elastase. 2. Treatment of pancreatic exocrine insufficiency: (1) Decrease in digestive enzymes: for pancreatic exocrine insufficiency caused by this factor, dietary habits should be improved in time, and exogenous digestive enzymes, such as pepsin and polypeptide tablets, should be supplemented if necessary. (2) Chronic pancreatitis: mainly due to the occurrence of a chronic inflammatory disease in the pancreas, when the condition is serious, it will lead to the internal and external secretion function of the pancreas is impaired, resulting in insufficient secretion. Oral cephalosporins should be taken as soon as possible to fight infection, and pancreatic enzymes should be supplemented if necessary, such as pancreatic enzymes enteric-coated capsules. If you have the above conditions, it is recommended to consult a doctor in time and analyze the cause of pancreatic exocrine insufficiency through various examinations, then carry out regular treatment and avoid unauthorized use of medication.