Short-term oral pantoprazole enteric-coated tablets will not cause the occurrence of polyps, long-term use has the possibility of polyps. Pantoprazole enteric-coated tablets are mainly proton pump inhibitors, which are often used in the clinic to treat gastric ulcers, duodenal ulcers, moderate to severe reflux esophagitis and other diseases. Short-term oral intake will not cause the occurrence of polyps, long-term use of proton pump inhibitors, can make the body low gastric acid state and gastrinogenemia, leading to an increase in the incidence of gastric polyps, especially fundic gland polyps. Side effects such as dizziness, headache, fatigue, rash, bloating, nausea, etc. may occur when taking pantoprazole, and care should be taken to ensure that it is not chewed or bitten into, and should be swallowed whole before meals. This drug is contraindicated in patients with severe hepatic or renal impairment, and should also be prohibited in patients who are allergic to pantoprazole. The above medication should be used under the guidance of a doctor, avoiding long-term self-medication.