How can breast paget disease be differentiated from eczema in terms of symptoms? Breast eczema, which usually occurs symmetrically on both breasts, is characterized by poorly defined margins, intermittent itching, and a tendency to become chronic. It can occur at any age, mostly in young women who are breastfeeding, and is effectively treated as eczema. In the case of paget disease of the breast, there are mostly unilateral eczema-like changes in the nipple that do not heal over time. The lesions are primary on the nipple and then develop towards the areola, with clear demarcation from the surrounding area. Later, indurated erosions of the affected nipple may occur, or a hard lump may be palpated in the breast. If diagnosed with nipple eczema, what occurs to be alert to the fact that it is actually breast paget disease? Since this disease can occur in early stages with chronic eczema disease both dermatitis, it is more difficult to distinguish. Therefore, patients with chronic skin lesions on the nipple and areola that do not improve significantly or do not improve after more than two weeks of treatment, but recur, should be alert to the differential diagnosis. If combined with nipple eczema as well as nipple masses, the diagnosis can be basically confirmed. What tests should be done to diagnose eczema patients with suspected paget disease of the breast? a, nipple discharge and skin exudate smear for cytological examination; b, lesion skin surface tissue section pathology; c, lesion skin epidermal tissue excision biopsy; d, breast lump puncture cell biopsy or excision pathology; e, molybdenum palladium film, sometimes can be found in the breast lumps, areola skin thickening and nipple depression and other manifestations. What other diseases should be differentiated from breast paget disease? It should also be differentiated from cystic adenoma of the nipple, which is relatively uncommon. It is easy to differentiate between early inflammation of the nipple and advanced nodular enlargement of the nipple. Is there a specific population for breast paget disease? Breast paget disease occurs most often in women between the ages of 50 and 80. Can men also get breast paget disease? Cases of paget disease of the breast have been reported in men, but the incidence is much lower than in women. Is breast paget disease contagious? The cause of breast paget disease is unknown and it is not usually contagious.