Sleeplessness in the first half of the night and in the second half of the night is a sleep disorder that is usually seen in patients who are going through menopause. It can also occur when the patient has depression. Menopause generally occurs in middle-aged and older people over 45 years of age. Most of the patients are between 45-55 years old, and women are more common. Patients can have difficulty sleeping or wake up early during sleep, which is mainly treated with oral glutamate, and can also be treated with oral meditation oral liquid or tranquilizer. If depression is the cause, the patient can also appear, not interested in anything, depressed mood, and may appear to reduce self-evaluation ability, and in serious cases, the patient can appear to be light-hearted accident. The main treatment is oral citalopram, but you can also take oral mirtazapine or Dextran, etc.