Whether or not lifelong medication is required after liver transplantation for biliary atresia is mainly related to the reaction produced by the body after liver transplantation and cannot be generalized. Biliary atresia, also known as congenital biliary atresia, is a rare bile duct disorder that occurs only in the infant and young child population. Surgical transplantation of a liver is usually required for its treatment, and since transplanted livers are susceptible to rejection of the host, antigens appear. Medication is required after the development of antigens, and if rejection persists over a long period of time, lifelong medication is required, while if rejection is insignificant or short-lived, lifelong medication is not required. After biliary atresia liver transplantation surgery, you need to have regular checkups and take anti-rejection drugs under the doctor’s guidance, strictly follow the doctor’s instructions to take the drugs, do not change or stop taking the drugs by yourself, and maintain a regular life, pay attention to rest, and avoid exertion.