Obese patients not only from the burden to the body, while its probability of cardiovascular and cerebrovascular diseases is significantly higher than that of people with normal weight, and with the increase of body mass index, the level of blood pressure is also higher. According to the latest Report on Nutrition and Chronic Disease Status of Chinese Residents, the overweight and obesity rates of residents ≥18 years old were 30.1% and 11.9% respectively in 2012, and the overweight and obesity rates of rural residents were lower than those of urban residents in 2012, but the rate of increase was greater than that of urban residents. According to the latest prevention guidelines for cardiovascular disease patients, this article details how to scientifically control weight. First, the weight should be controlled in what range Measurement of obesity indicators are more, of which the most commonly used in the clinic is the body mass index [BMI, calculated as BMI = weight (kg) ÷ height 2 (m2)], the guidelines recommend that people with a normal body weight should pay attention to keep in the normal range (18.5-24kg/m2). Overweight and obese people should try to reduce their weight, strive to reach the normal range, and reduce other risk factors such as hypertension, dyslipidemia, diabetes mellitus, etc., to comprehensively reduce the risk of cardiovascular disease. Overweight and obesity, including central obesity characterized by abdominal fat accumulation, are potential risk factors for hypertension, diabetes, cardiovascular disease and other metabolic diseases. The focus of China’s adult BMI proposed by the China Obesity Working Group is: 18.5kg/m2 ≤ BMI < 24.0kg/m2 for normal weight range, 24.0kg/m2 ≤ BMI < 28.0kg/m2 for overweight, and BMI ≥ 28.0kg/m2 for obesity. Classification of adult waist circumference in China: normal range male <85cm, female <80cm. when waist circumference 85cm ≤ male <90cm, 80cm ≤ female <85cm defined as pre-central obesity. When the waist circumference of men ≥ 90cm, women ≥ 85cm defined as central obesity. Guidelines suggest that weight should be kept in the normal range. Second, what are the methods of scientific weight control Weight loss can significantly reduce the level of cardiovascular disease risk factors in overweight or obese people, so that the risk of cardiovascular disease is reduced. For overweight or obese individuals, the first screening should clarify the presence of endocrine diseases and factors that may cause secondary obesity, such as hypothalamic/pituitary infections, tumors, trauma, hypercortisolism, hypothyroidism or hypogonadotropic hypogonadism, and insulinoma. Clarify the presence of other clinical risks, such as diabetes, cardiovascular disease, sleep apnea syndrome, etc. Consult a specialist if the above conditions are combined, and actively treat the primary disease and corresponding risk factors. For overweight and obese individuals, individualized interventions and treatments should be considered. The general principles of intervention include strict lifestyle changes, rationalization of diet, strengthening of physical activity and exercise, health education and psychotherapy. For obese individuals who have failed to take the above principles of intervention for 6 months, medication-assisted treatment may be considered. For individuals with BMI ≥35.0kg/m2, risk factors or serious complications, surgical treatment may be considered.