In our country, cardiovascular and cerebrovascular disease has become one of the diseases that seriously jeopardize the health and life of our people, and the data show that in the past 30 years, the mortality rate, morbidity and prevalence of cardiovascular and cerebrovascular disease in our population have been on the rise, and the age of onset has advanced. In order to reduce the incidence of cardiovascular and cerebrovascular diseases, to achieve the purpose of preventing the disease before it occurs, it is very important to increase physical exercise to alleviate. This article will be combined with the latest cardiovascular disease prevention guidelines to explain how patients with cardiovascular disease scientific “open legs”. First, why should people with cardiovascular disease exercise? The guide points out that lack of physical activity has become one of the major risk factors for cardiovascular disease death and disease burden in China. A survey in China shows that the amount of physical activity of residents aged 18 to 60 years old has shown a significant downward trend, in which the decline in occupation-related physical activity is the most obvious, while the level of physical activity is also at a lower level. Increasing physical activity can result in significant health benefits in the short term, such as reducing anxiety, improving sleep, and lowering blood pressure. The results of a 5.8-year follow-up study in China showed that increased physical activity can lead to a lower risk of developing hypertension. Adherence to regular physical activity improves cardiorespiratory fitness, increases muscle strength, and reduces all-cause and cardiovascular deaths by 20% to 30% in all age groups. There is a significant association between cardiovascular health and the intensity, frequency, duration, and total amount of physical activity, and analysis of our cohort study showed that maintaining ≥150 minutes of moderate-intensity physical activity per week or ≥75 minutes of vigorous-intensity physical activity per week reduces cardiovascular disease incidence in adults by 1.4%. Meanwhile, the 2018 U.S. Physical Activity Guidelines also emphasize that increasing exercise and reducing sedentary behavior is applicable to almost everyone, and that even a small increase in physical activity can provide health benefits. How can people with cardiovascular disease scientifically “get their legs moving”? The basic goal of physical activity for adults is to increase exercise and reduce sedentary behavior. For sedentary adults, even small amounts of moderate or vigorous physical activity can have health benefits. A healthcare professional or exercise specialist can guide the individual to set the right level of physical activity (intensity, duration, and frequency of physical activity) for his or her situation, inform about the dangers of inactivity, and recommend the appropriate type of activity, preferably in conjunction with daily lifestyle (e.g., hiking, biking, etc.) so that it can be adhered to over the long term. Specific recommendations: 1. Recommend that healthy adults should have at least 150 minutes of moderate-intensity aerobic physical activity per week, or at least 75 minutes of vigorous-intensity aerobic physical activity per week, or an equal amount of a combination of the two intensities of activity; 2. In order to receive additional health benefits, recommend that healthy adults should increase their aerobic physical activity to reach 300 minutes of moderate-intensity per week or 150 minutes of vigorous-intensity aerobic physical activity per week, or an equal amount of a combination of the two intensities; 3. Aerobic activity should last for more than 10 minutes each time, four to five days a week, if possible; 4. Elderly people aged 65 years and older, people with chronic diseases or people with disabilities, even if they can’t reach the level of physical activity of a healthy adult, should insist on physical activity according to their physical condition, and avoid being sedentary; 5. Individuals who are accustomed to sitting for a long period of time and who have cardiovascular risk factors should consider taking a few precautionary measures before engaging in strenuous physical activity. clinical assessment of health status should be considered before engaging in strenuous exercise. Physical activity modalities for older adults should include balance training in addition to aerobic exercise and strength training to prevent falls. In addition, chronically ill or disabled individuals should be instructed by a healthcare professional or exercise specialist to remain physically active according to their health status and to avoid sedentary behavior.