Progesterone shots for pregnant women are not harmful. The progesterone injection is progesterone, this drug is a natural progesterone, is extracted from plants, if there is a pre-eclampsia, you can use this drug to protect the fetus, can increase the progesterone height, can also release the uterine cramps, for the preservation of the fetus is very effective, and also does not affect the fetal development. If this drug is injected for a long time, it will cause local redness and swelling as well as hard knots, so in the process of injection, local hot compresses with hot towels should be applied every night to reduce the symptoms.