If patients feel tired and uncomfortable in the heart, the following diseases should be considered: 1, coronary atherosclerotic heart disease, unstable angina pectoris, arrhythmia, myocarditis, infective endocarditis, hypertrophic obstructive cardiomyopathy, the above cardiogenic diseases, also called organic diseases of the heart, can be induced by overexertion and lead to the appearance of uncomfortable symptoms within the heart. 2, for chronic heart failure, also 3. respiratory diseases, such as chronic bronchitis, bronchial dilatation, chronic pulmonary heart disease, can also cause the heart to feel uncomfortable when overworked. 4. some hypertension can also cause the symptoms of uncomfortable body when overworked. 5. some non-organic factors, such as mental tension, anxiety, and work stress can cause the symptoms.