Sperm DNA fragmentation caused by DNA breakage during sperm production, i.e. sperm maturation, or double-stranded breaks under the action of undesirable factors in certain environments and oxidative free radicals of the organism, may generally form good embryos. It may affect every stage of cell development through defects in chromosomal abnormalities cell proliferation and delayed cell division. Recent studies have also shown that a high rate of sperm DNA fragmentation affects the rate of formation of good quality embryos and does not mean that good quality embryos cannot be obtained. Therefore, a high sperm fragmentation rate may result in obtaining quality embryos, but the efficiency of obtaining quality embryos is likely to decrease, so patients with a high sperm fragmentation rate may obtain few quality embryos or fail to obtain quality embryos. Reducing male sperm DNA fragmentation is also a high concern in addressing male infertility. In addition, quality embryos are only morphologically assessed in the usual sense, and even genetically normal embryos do not provide complete assurance of the impact of sperm DNA fragmentation on assisted reproduction offspring. Therefore, when possible, reducing sperm DNA fragmentation is also necessary.