It is not possible to speculate on the exact life expectancy of biliary cirrhosis. Biliary cirrhosis is categorized into primary and secondary. The prognosis of patients with primary biliary cirrhosis varies greatly and is unpredictable, so it is impossible to accurately determine life expectancy; secondary biliary cirrhosis has the possibility of being cured if the cause of the extrahepatic bile duct obstruction can be found. Primary biliary cirrhosis can be caused by chronic non-suppurative cholangitis of the intrahepatic bile ducts and is associated with genetic factors, environmental factors, and autoimmune reactions. Therefore, primary biliary cirrhosis is more difficult to treat and affects the survival rate. Among them, primary biliary cirrhosis due to immune factors has a greater impact on survival. Secondary biliary cirrhosis, on the other hand, is associated with two factors: long-term extrahepatic bile duct obstruction and biliary tract upstream infections. The more common ones are biliary stones and tumors. If the cause of the disease can be identified as early as possible and after surgical treatment, the prognosis is usually good and life expectancy will not be affected. When biliary cirrhosis occurs, it is recommended to consult a doctor in time and follow the doctor’s instructions for further examination, so that the cause can be clarified with the doctor’s help and targeted treatment or therapy can be carried out.