Adrenal nodules may cause high blood pressure. If adrenal nodules secrete aldosterone, steroid hormones and catecholamines, it may cause hypertension. 1. Aldosterone: The secretion of large amounts of aldosterone by adrenal nodules may cause the emergence of primary aldosteronism, which in turn causes an increase in the level of aldosterone hormone in the blood, and induces an increase in blood pressure and a decrease in blood potassium. 2. Steroid hormones: when adrenal nodules secrete a large amount of steroid hormones, it may cause Cushing’s syndrome, the main clinical manifestations of which are high blood pressure, buffalo back and full moon face. 3. Catecholamines: the main physiological role of catecholamines is to stimulate the α-receptor of blood vessels, which can easily lead to vasoconstriction and thus may induce hypertension. If patients find adrenal nodules, it is recommended to go to regular hospitals in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.