Clotrimazole cream is an antifungal drug mainly used for skin infections and vulvovaginitis. When using it, the skin should be washed and clotrimazole cream should be applied to the affected area, the specific dosage must follow the doctor’s prescription or instructions. In addition, if there is a burning sensation, redness or swelling at the site of application, the drug should be discontinued and the drug should be washed locally and, if necessary, the doctor and pharmacist should be consulted. If this drug is used for pregnant and nursing women, it must also be used under the guidance of a doctor. In conclusion, Clotrimazole cream is a topical medication mainly used for vaginitis of the skin and vulva.