The advantages of bone density injections are greater anti-osteoporotic effect, lower incidence of adverse effects, lower cost required for a course of treatment, and better compliance. The disadvantages are the possibility of abnormal liver function, gastrointestinal reactions, and electrolyte disturbances. Bone density shots are therapies to combat osteoporosis by infusing the drug zoledronate, a bone resorption inhibitor and a new anti-osteoporosis drug that is particularly effective in reducing fractures in key areas such as the vertebrae, hip and distal ulnar radius. Zoledronate only needs to be infused once a year to be more effective than first-generation anti-osteoporosis drugs. However, bone density injections may increase the burden on the liver, causing temporary liver function abnormalities, as well as gastrointestinal reactions such as nausea and vomiting, and may also cause electrolyte disorders such as decreased blood calcium in the elderly. Bone density shots for the elderly need to be administered under the guidance of a medical professional.