Probiotics can help regulate indigestion to a certain extent. Probiotics are mainly Bacillus licheniformis, Bifidobacterium bifidum, Lactobacillus acidophilus, etc. These probiotics can improve the barrier of the intestinal mucosa, prevent the invasion of pathogenic bacteria, inhibit the growth of pathogenic bacteria, can be used to prevent and control constipation, intestinal dysfunction and other diseases, but also can play a role in regulating indigestion. Dyspepsia can be divided into functional dyspepsia and organic dyspepsia, functional dyspepsia can follow the doctor’s instructions to use digestive enzyme preparations such as compound digestive enzymes, mitomycin pancreatic enzyme tablets and other digestive enzyme preparations, gastric stimulation medication, such as domperidone, etc. Organic dyspepsia needs to be directed at the cause of the treatment. Therefore, there is no cure for indigestion by taking probiotics alone. Patients who need to treat dyspepsia should go to the hospital and ask the doctor to make a judgment and give a treatment plan.