In hepatitis B five tests, items 1, 3 and 5 are positive, and after treatment, the rate of conversion to items 1 and 5 is positive, that is, hepatitis B triple positive to hepatitis B minor bi-yang, and the rate of conversion is generally low. When Hepatitis B major triple positive turns into Hepatitis B minor bi-yang, the main change is that the E antigen turns negative, which means that the immunity of the organism is being strengthened, thus making the virus in the organism to be gradually cleared; in addition, if the immunity of the organism is not strong enough, it is possible to turn to major triple positive again; if the immunity of the organism is strong enough, it is possible to turn to minor bi-yang. For Hepatitis B small two-positive, it is necessary to combine liver function and liver and gallbladder ultrasound and other indicators to assess the change of the condition. If it is in the active stage of hepatitis, it is necessary to receive antiviral treatment, such as entecavir and tenofovir, etc.; however, the purpose of the treatment is only to control the deterioration of the condition and inhibit the replication of the virus, which is generally difficult to clear the Hepatitis B virus, and so it can not be converted into a negative condition. In addition, the application of all the above drugs carries certain risks, and patients need to be guided by specialized doctors.