Stage IV bone metastasis of lung cancer is relatively serious and belongs to the advanced stage of tumor. After stage IV bone metastasis of lung cancer, generalized pain may occur, which is still relatively strong, and even pathological fracture may occur, which are all manifestations of bone metastasis, so stage IV bone metastasis of lung cancer is relatively serious. For patients with stage IV lung cancer bone metastasis, systemic therapy, including systemic chemotherapy and targeted therapy, immunotherapy if possible, local radiotherapy or radiofrequency ablation, etc., can be used to prolong the survival of patients. Patients with stage IV lung cancer bone metastasis should consult doctor in time, actively cooperate with doctor’s treatment, pay attention to dietary care, give high nutritional and easy to digest food, eat less and more frequent meals, and the caregivers can instruct patients to divert their attention and relaxation training in order to reduce the intensity of pain.