A normal sinus beat followed by a ventricular pre-systole is called ventricular pre-systolic dysthymia, or premature ventricular dysthymia, and can be seen in physiologic conditions and in patients with organic heart disease. The decision to treat or not to treat is based on the patient’s symptoms and the presence or absence of organic heart disease. 1. Patients without organic heart disease, no obvious symptoms or mild symptoms do not need drug treatment. If the patient’s symptoms are obvious, the treatment is aimed at eliminating the symptoms. The drugs should be propranolol hydrochloride tablets, diltiazem, propafenone, etc. . Catheter ablation can be considered for a small number of patients who are not well treated with antiarrhythmic drugs. 2. Patients with organic heart disease, in principle, only deal with the heart itself, do not need to treat ventricular pre-systole drugs, if the symptoms are obvious, can use metoprolol tartrate tablets, amiodarone and so on. For patients with acute myocardial ischemia or infarction combined with ventricular pre-systolic dystocia, thrombolysis or interventional therapy is preferred to restore the blood flow supply to the heart. If the ECG results are abnormal, it is recommended to consult a doctor to clarify the cause of the disease and provide targeted treatment or therapy.