Female patients with SLE can have intercourse during the stable phase of the disease, but it is generally not recommended during acute exacerbations. SLE is an autoimmune disease, which is a kind of rheumatic disease with various clinical manifestations and can involve many systems and organs of the body. In many cases, the diagnosis of SLE is confirmed by the presence of multiple positive antibodies during antinuclear antibody tests, which occur in the middle and late stages of pregnancy or after the birth of a child. The specific pathogenesis of SLE is not well understood, so there is no cure for SLE, and long-term maintenance treatment is mainly with glucocorticoids and immunosuppressants.