Most of the liver is situated in the right quarter-rib region and the supra-abdominal region, and only a small portion in the left quarter-rib region. Most of the anterior part of the liver is covered by the ribs, and only a small portion of it is exposed between the left and right rib arches in the supra-abdominal region under the raphe and in contact with the anterior wall of the abdomen; the diaphragm is located above the liver, below the right lobe of the liver, adjacent to the right curvature of the colon anteriorly, in the middle near the hepatic hilum close to the upper curvature of the duodenum, adjacent to the right adrenal glands and the kidneys posteriorly, below the left lobe of the liver and the anterior wall of the stomach, and above the posteriorly, adjacent to the esophagus. The liver is the largest gland in the human body and the largest substantial organ, it is the most active organ in the body’s metabolism, it is involved in the synthesis, transformation and decomposition of proteins, lipids and other substances, it is also involved in the transformation and detoxification of hormones and medicines, it also secretes bile and participates in the digestion and decomposition of lipids, and it has the important functions of phagocytosis, defense and hematopoiesis in embryonic period. Abnormal liver function or discomfort in the liver area, it is recommended to consult a doctor in time for a clear diagnosis and active treatment.