Trisomy 21, also known as Down syndrome, is characterized by a child’s intellectual backwardness, delayed physical development compared to normal children, significantly lower length and weight during growth and development, delayed physical and motor development compared to normal children, a special facial appearance, and a variety of malformations and disabilities such as congenital heart disease. The most prominent and serious manifestation of this disorder is intellectual backwardness, which becomes more pronounced with increasing age. Once a child with Down’s syndrome is born, it can be a huge burden to the family, so it is important to be screened for Down’s syndrome during pregnancy.