Irregular life can cause digestive system diseases, respiratory system diseases, circulatory system diseases, neurological system diseases and endocrine system, five major system diseases. Digestive system diseases caused by irregular life include digestion and absorption, which can lead to abdominal distension, nausea, vomiting, anorexia, especially anorexia of oil and grease, along with constipation, digestive malabsorption, and occasionally diarrhea. Second, common circulatory system diseases include coronary atherosclerotic heart disease, unstable angina pectoris, myocarditis, cardiomyopathy and other conditions that are prone to occur. At this time, the immune function of large arteries and capillary endothelial cells becomes weak, especially susceptible to coronary heart disease and myocardial infarction. Third, for respiratory system diseases often have upper respiratory tract infections, pneumonia, tonsillitis, pharyngitis and other diseases susceptible. Fourth, common neurological diseases include poor sleep quality due to irregular life, memory loss, insomnia, forgetfulness, anxiety, etc. Fifth, due to irregular life common endocrine system has endocrine dysfunction, women often have menstrual disorders and other conditions.