When eGFR is low and urea is high, it indicates that renal insufficiency may exist, and a treatment plan needs to be formulated according to the eGFR value and comorbidities. If eGFR is greater than 15ml/min, renal integrated therapy is generally needed, such as correcting anemia, calcium and phosphorus disorders, acidosis, and lowering blood pressure, etc.; if eGFR is less than 15ml/min renal replacement therapy may be needed.
Reduced eGFR (estimated glomerular filtration rate) reflects the reduced glomerular filtration rate, which can lead to elevated urea and creatinine. eGFR is mainly an indicator for evaluating the renal function of chronic kidney disease, and according to the value of eGFR, chronic kidney disease is divided into 5 stages.
If it is greater than 15 ml/min, integrated nephropathy treatment is generally needed, mainly to control blood pressure, reduce urinary protein, and treat various complications such as renal anemia, electrolyte disorders, secondary hyperparathyroidism, acidosis, and so on; if it is less than 15 ml/min, renal replacement therapy, such as hemodialysis, peritoneal dialysis, etc., may be needed.
Patients with low eGFR and high urea are recommended to consult regular hospitals and standardize treatment under the guidance of physicians.