Subcutaneous fibroma generally refers to dermatofibroma. Patients with dermatofibroma can take medication, physical therapy and surgery to improve the prognosis. 1. Drug treatment: For patients with dermatofibroma with multiple skin lesions, corticosteroid hormone, such as trimethoprim, can be injected into the lesion area, and the lesions can be reduced through drug treatment. 2. Physical therapy: for the lesions that are protruding from the skin surface or subject to repeated trauma, patients can take liquid nitrogen cryotherapy, carbon dioxide laser therapy, pulsed dye laser, etc., which can make the local lesions subside and have a better therapeutic effect. 2. Surgical treatment: for the non-surgical treatment is ineffective, patients can take surgical treatment, usually the local lesions can be removed, so as to improve the prognosis. Once patients are diagnosed with dermatofibroma, they can take into account their own situation, as well as their personal needs, and ask the doctor’s advice. In daily life, it is necessary to keep the local skin clean to avoid secondary infection.