Clinical staging of chronic renal failure (chronic renal insufficiency) (domestic) Clinically, according to the different degrees of renal impairment, it is divided into four stages according to domestic standards: 1. Compensatory stage: At this time, endogenous creatinine clearance (Ccr) is reduced, but above 50 mL/min, blood creatinine is below 178 μmoL/L, blood urea nitrogen is below 9 mmoL/L, and there are generally no clinical symptoms, also known as renal The period of decompensated renal reserve function. 2. Decompensated stage: Ccr is 25-50mL per minute, blood creatinine is elevated to 178μmoL/L (2mg/dL) or more. The blood urea nitrogen reaches 9mmoL/L (25mg/dL) or more, except for mild anemia, gastrointestinal symptoms, increased nocturia without obvious discomfort, but the clinical symptoms worsen when exertion, infection, blood pressure fluctuations or eating too much protein, also known as the azotemia phase. 3, the stage of failure: Ccr 10-25mL per minute, blood creatinine is 221-442μmoL/L, blood urea nitrogen 17,9-21,4mmoL/L, most of them have more obvious abdominal symptoms and anemia symptoms, mild metabolic acidosis and abnormal calcium and phosphorus metabolism, but No obvious disorders of water and salt metabolism, also known as early uremia. 4, uremic phase: blood creatinine>442μmoL/L blood urea nitrogen>21,4mmoL/L, often appear various uremic symptoms, such as obvious anemia, severe nausea, vomiting and various neurological complications, and even coma, obvious water and salt metabolism and acid-base balance disorders. When Ccr <10m1 per minute and blood creatinine >707μmoL/L is called end-stage, also called advanced uremic syndrome.