24-hour urine protein 0.3g is not serious. Under normal circumstances, the kidneys can also lose some protein, but the amount is relatively small, 24-hour urine protein quantitative generally below 0.15g, if more than 0.15g is abnormal, 0.3g more than 0.15g, but not a lot, is not serious, this situation is mainly seen in chronic glomerulonephritis. The increase of urinary protein can also cause damage to the kidneys, this time you can use some drugs to reduce urinary protein, such as Irbesartan, Perindopril this kind of drug. Some proprietary Chinese medicines are also effective in reducing urinary protein, such as huangkui capsule. To dynamically review the 24-hour urine protein quantitative, usually once a month. If the quantitative increase of urine protein gradually, it is necessary to apply hormone treatment, such as prednisone or Medrol, and if necessary, you can also consider applying immunosuppressants, such as cyclophosphamide.