To do plasma replacement to establish vascular access, the need for blood perfusion, the use of blood perfusion device, blood tubes, but also the replacement fluid, replacement fluid, fresh frozen plasma, saline, Ringer’s solution, albumin, etc., such as all add up to do a plasma replacement of about 6,000 yuan – 8,000 yuan, double plasma replacement requires a small amount of plasma, the cost of a higher, need to be 10,000 yuan. The specific cost is also related to the level of the hospital, and the charges are different between secondary and tertiary hospitals. It is also related to the use of perfusion, the type of plasma separator used, and the price of the blood line.