Lumps on the skin with blood and water when pressed out are considered to be boils, carbuncles, acne, and so on. The main treatments are medication, surgery, etc. The appropriate medication should be chosen according to the specific cause. 1. boils: boils are acute purulent inflammation that occurs in the hair follicles and deep surrounding tissues, most of them are caused by Staphylococcus aureus infections, you can apply ichthyolite ointment, tincture of iodine, etc., and locally, you can apply mupirocin ointment, fusidic acid cream, and you can orally take amoxicillin, cefixime for the more serious symptoms, and you need to make incision and drain the area if it has already become pus-filled and broken down. 2. Carbuncle: more than one scabies will form carbuncle, can be deep into the subcutaneous tissue, there will be multiple pus, there will be pus and bloody secretion, you can apply mupirocin ointment, erythromycin ointment, you can also take antibiotics, such as roxithromycin, clarithromycin, late pus has broken through the incision and drainage in a timely manner. 3. acne: acne is a chronic inflammation of the sebaceous glands of the hair follicles, mainly androgen levels and sebum secretion increase related to the application of retinoic acid drugs, such as isotretinoin, tazarotene, you can also choose benzoyl peroxide, azelaic acid, if combined with bacterial infections, you can apply erythromycin ointment, clindamycin ointment. Skin lumps pressed out with blood and water should be timely consultation, clear cause, under the guidance of the doctor standardized treatment, the above medication should be used in accordance with medical advice.