The sequelae of POEM surgery for pancreatic achalasia can be seen as gastroesophageal reflux and rupture of esophageal mucosa. 1. Gastroesophageal reflux: pancreatic achalasia means that the sphincter of the cardia under the esophagus can not be effectively relaxed during swallowing, resulting in the retention of food in the esophagus.POEM surgery is a transoral endoscopic esophageal sphincterotomy, and there is a poor recovery of esophageal sphincter and impaired cardia function after the surgery, which results in the emergence of gastroesophageal reflux, which can be alleviated by taking magnesium alumina carbonate tablets according to the doctor’s prescription. 2. Rupture of esophageal mucosa: During POEM surgery, it is necessary to cut the esophageal mucosa layer, therefore, there are cases of rupture of esophageal mucosa after surgery. After clear diagnosis, antibiotics can be used to control the infection, and if necessary, laceration repair can be done. Drugs need to be rationally applied according to medical advice.