Itchy and ulcers in the middle of the toes are usually seen in tinea pedis, which is caused by fungal infection, and the treatment is divided into general treatment and drug treatment. 1. General treatment: patients should maintain personal hygiene, keep feet dry and breathable, pay attention to change shoes and socks frequently, avoid scratching and stimulation. 2. Drug treatment: when there is impregnated erosion, you can first use 3% boric acid solution, 0.1% isacridine and other wet compresses, to be no obvious exudation after the patient can use antifungal drugs to smear, such as miconazole nitrate, naftifine ketoconazole, etc. External use. If necessary, oral medication can be carried out, such as oral terbinafine hydrochloride tablets. Specific medication should be carried out under the professional guidance of the physician, to avoid unauthorized use of drugs. Tinea pedis is recommended to go to the hospital in time to avoid delaying the condition.