Itchy skin and allergies can be treated by sedative, intramuscular, oral and topical medications, which are selected according to the specific situation and severity as follows: 1. sedative medications: compound glycopyrrolate injection; in severe cases, glucocorticoid injections such as methylprednisolone injection and dexamethasone injection; 2. intramuscular medications: glucocorticoid injections such as dexamethasone injection, and chlorpheniramine maleate injection; 3. 3, oral drugs: antihistamine drug injection, including levocetirizine hydrochloride capsule, loratadine citrate capsule, epinastine hydrochloride capsule, loratadine capsule, etc., can also be taken orally compound glycopyrrolate capsule or compound glycopyrrolate tablets; 4, topical drugs: including glucocorticoid ointment, such as hydrocortisone butyrate ointment or mometasone furoate cream, etc.