LSIL is also a low-grade cervical intraepithelial neoplasia and it is difficult to predict how long it will take for the cancer to develop. It may not become cancerous, it may take 3-5 years, or it may become cancerous in about 10 years. LSIL resolves spontaneously in about 60% of cases, and those with LSIL or less on cytology may be followed up with observation only. Treatment is appropriate if the lesion develops during follow-up or persists for 2 years. If a patient develops complications of high-risk human papillomavirus infection, cancer is likely to develop in about 10 years. Patients whose test results remain LSIL after cervical conization may develop cancer within 3-5 years. The process of low-grade cervical intraepithelial neoplasia is relatively slow, and regular checkups are recommended. The pathologic results of screening will not change for 1-2 years, and the need for surgical resection may also be an option after LSIL lesions are removed, with less likelihood of cancer occurring after surgical resection.