There are many reasons why the hands do not obey, considering transient cerebral ischemia, cerebral hemorrhage, Parkinson’s disease and other causes. 1. Transient cerebral ischemia: there will be sudden symptoms of upper limbs and lower limbs without domination or paralysis, often accompanied by dizziness, nausea, vomiting and other symptoms, which are caused by transient impairment of neurological function due to focal ischemia of the brain. 2. Cerebral hemorrhage: cerebral hemorrhage may appear numbness and weakness in the upper and lower limbs, which may be accompanied by headache, slurred speech, difficulty in walking, etc. It is caused by blood flow after rupture of cerebral blood vessels, and is related to various cardiovascular and cerebrovascular diseases, such as aneurysm, post-infarction hemorrhage, and so on. 3. Parkinson’s disease: with age, some middle-aged and old people’s nervous system will appear degenerative diseases, tremor, muscle stiffness, limbs do not obey the command of the symptoms, this situation may be Parkinson’s disease. If the hands do not obey, you should consult with the hospital in time and follow the doctor’s instructions for examination and treatment.