The prognosis of thyroid cancer is not related to male or female, but to the type of disease. Follicular thyroid cancer and papillary carcinoma have a better prognosis, while medullary thyroid carcinoma does not have a better prognosis than papillary carcinoma. The prognosis of medullary thyroid carcinoma is not as good as that of papillary carcinoma. Undifferentiated carcinoma is less common in clinic and generally has a poor prognosis. Papillary and follicular thyroid carcinomas are relatively mild and have a good prognosis after treatment. Medullary carcinoma of thyroid is prone to hematogenous metastasis and lymph node invasion in the neck, so its prognosis is not as good as that of papillary carcinoma. Undifferentiated carcinoma is relatively rare in clinic nowadays and has a higher probability of death, so its prognosis is not very good, and its 5-year survival rate is only 5%~15%. The prognosis of male thyroid cancer, no matter what pathologic type, is related to the stage to a certain extent. Therefore, one should have regular physical examination of the thyroid gland, and achieve “early detection, early diagnosis, and early treatment” for thyroid cancer, which can improve the prognosis.