The two sides of the buttocks generally refers to the buttocks, the two sides of the buttocks long small acne is usually caused by folliculitis, chronic eczema and other diseases, can be taken in accordance with the doctor’s instructions for general treatment, local medication, oral medication, etc., to alleviate the symptoms. 1. Folliculitis: is caused by pathogen infection, can occur in any hair follicle parts of the body, such as the head, face, neck, buttocks, etc., lesions manifested in the formation of red papules around the hair follicles, and accompanied by red, swelling, pain and other inflammatory reactions. Local skin cleanliness should be ensured and scratching of the affected area should be avoided. For mild cases, antibiotics such as mupirocin ointment, fusidic acid cream and clindamycin gel can be applied as prescribed by the doctor. For severe cases, antibiotics such as amoxicillin and cefuroxime can be taken orally. 2. Chronic eczema: can also lead to pimples on both sides of the buttocks, and pimples grow on the infiltrative dark red spots, local skin hypertrophy, surface roughness, can be accompanied by obvious itching. Suspected causes should be searched for and avoided, and topical glucocorticosteroids should be used as prescribed by the doctor, such as dianabed cream, mometasone furoate cream, halometasone cream, etc.. For severe itching, antihistamines such as cetirizine and loratadine can be taken orally to relieve itching, and for secondary infections, antibiotics such as cephalosporin and penicillin for sensitive bacteria can be used. In addition, diseases such as milia can also cause small pimples on both sides of the buttocks, it is recommended to go to the hospital in a timely manner to identify the cause of the disease, and then receive treatment as soon as possible.