Fluorescence in situ hybridization technology can check many kinds of diseases, just a biological test of technology, in fact, not only in the human body can be used, in many animal and plant detection tests can be applied, specifically to the diagnosis of common diseases, the most commonly used is definitely the tumor, especially malignant tumors, for example, are as follows: a. Breast cancer overexpression of the human epidermal growth factor receptor-2 is often used fluorescence Fluorescence in situ hybridization is often used to make the final judgment. The mutation status of mesenchymal lymphoma cumulative enzyme in the middle of lung cancer, and whether there is fusion of mutations. Third, sometimes testing techniques are used to detect many sarcomas, such as Ewing’s sarcoma or mucinous liposarcoma, and so on. Fourth, reproductive genetic diseases, such as trisomy 21, such genetic diseases are often used this technology. In conclusion, this technique is mainly used to detect the DNA of faulty cells and can be used for many diseases.