Common drugs that lower heart rate without lowering blood pressure include digitalis, ivabradine, and so on.
1. Digitalis drugs: that is, cardiac glycosides, this class of drugs common digoxin, hairy flower glycoside C, digitalis glycosides, etc., with positive inotropic, negative frequency of the role of blood pressure can be elevated at the same time to reduce the heart rate. Contraindications to this class of drugs are atrioventricular block, preexcitation syndrome with atrial fibrillation or atrial flutter. Adverse reactions are digitalis toxicity, gastrointestinal reactions.
2. Ivabradine: it is the only selective inhibitor of cyclic nucleotide-gated channels in the clinic at present, and it is a pure heart rate-slowing drug, which can slow down sinus heart rate and has no obvious effect on blood pressure. Adverse reactions are blurred vision, headache, dizziness, etc., and occasionally palpitations and nausea. Contraindications are cardiogenic shock, acute infarction, severe hypotension, severe hepatic insufficiency and so on.
The above drugs need to be applied under the guidance of a doctor, do not use drugs without authorization to avoid serious adverse reactions.