Stinging sensation at the end of urination is seen in female patients and is mostly caused by acute cystitis. Acute cystitis is a common urinary tract infection in female patients, it is generally divided into acute simple cystitis and recurrent cystitis, the causative bacteria are mostly Escherichia coli, accounting for about 75% or more, more common in female compatriots. Because the female urethra is shorter than the male urethra and is close to the anus, E. coli can easily invade. When acute cystitis occurs, patients usually have urinary frequency, urgency, painful urination, discomfort in urination, pain in the lower abdomen, and terminal hematuria. At the end of urination, there will be a stinging or burning sensation in the urethra. If this symptom occurs, it is best to go to the hospital for a routine urine test. Generally speaking, the number of white blood cells in the routine urine will increase, so consider acute cystitis. You must drink more water, keep your perineum clean and hygienic, take oral levofloxacin for three days, and eat less spicy and stimulating food.