In general, the factors associated with the development of rhinosinusitis in children are similar to those in adults, but the younger age of children, the developing sinuses, and the immature immune system make the factors associated with rhinosinusitis in children have their focus and tendency compared to adults, and the following related factors may be important for the development and pathophysiology of rhinosinusitis in children: 1. important etiology. More than one-third of children with chronic asthma suffer from rhinosinusitis. Adenoid hypertrophy is considered to be a hiding place for bacteria, and its hypertrophy can cause nasal obstruction, retention of nasal secretions, and decreased cilia activity. 4, humoral immune defects and diseases Immune system of children before the age of 10 is not mature. 5. Gastroesophageal reflux disease For children, gastroesophageal reflux is prevalent and physiological in nature. Only frequent occurrence or persistence for a longer period of time can cause nasal inflammation and edema, which in turn can predispose to rhinosinusitis.