Taking TB medication does not affect HIV testing. There are many ways to test for HIV, including routine immunologic tests as well as blood biochemistry and virus-specific antibody tests. The majority of TB drugs are antimicrobials. For example, at the level of immunological examination, since anti-tuberculosis drugs do not affect the excessive fluctuation of the number of CD4+ lymphocytes in the body, therefore, at this level, tuberculosis drugs will not affect the results of HIV testing. The antibody test of HIV is the gold standard for the diagnosis of HIV infection, which mainly relies on chemiluminescence method or immunofluorescence method for the initial screening/review of HIV p24 antigen and gp120 antibody in the serum, whereas tuberculosis drugs do not have any special influence on the structure of the virus and its load, and therefore will not affect the test results. Therefore, from a variety of perspectives, taking tuberculosis drugs will not affect the test results of AIDS, if you suspect that you are infected with HIV can go to a professional disease prevention and control center for professional testing.