Micropapillary lung adenocarcinoma is a pathological subtype of lung adenocarcinoma, which manifests as a tumor filled with clustered, filamentous, or elongated papillae, which are free of fibrovascular axes, and has a low incidence of . It is most common in middle-aged and elderly people and has a poor prognosis, even at an early stage, with the shortest recurrence-free survival time after surgery of all types. Micropapillary lung adenocarcinoma, also known as micropapillary-dominant adenocarcinoma, is an invasive adenocarcinoma that has several pathologic subtypes, including alveolar, adnexal, papillary, and micropapillary. The incidence of micropapillary lung adenocarcinoma is low, and the micropapillary component has a certain relationship with the prognosis of lung cancer. The lesions are mostly located in the periphery of the lungs, and solid nodules predominate, which are characterized by small lesions and large metastases. Most of them are found in the advanced stage, and will show multiple lymph node metastases, or extensive carcinomatous lymphadenocarcinoma of the lungs, with a poorer prognosis. In recent years, targeted therapy and immunotherapy have been gradually applied to the comprehensive treatment of various tumors. If the stage of lung cancer is clear, comprehensive treatment can be adopted according to the doctor’s instruction. It is recommended to consult the hospital, please follow the doctor’s instruction.