The incidence of primary open-angle glaucoma is 0.57% over 30 years of age, and the incidence increases with age, but it can also develop at 20 to 30 years of age, or even at 10 years of age. Primary open-angle glaucoma is a hereditary and familial disease, and the exact mode of inheritance is not known, most likely being polygenic and multifactorial. It has a high prevalence of 5%-19% in consanguineous families and up to 50% in those with a family history. The population is susceptible to open-angle glaucoma with the following conditions: 1. High intraocular pressure. This is the first risk factor. Although there is no glaucomatous damage in the early stages, the possibility of glaucomatous damage increases as the duration of high intraocular pressure increases and the IOP base value continues to rise. 2. Optic papillary sagging. This is the second risk factor, and large, deep pits are poorly tolerated by pressure. The progressive enlargement of the sulcus is the most important risk factor and can occur before visual field defects. These people need to be regularly examined for optic disc traps and visual fields, and treated as soon as optic nerve damage occurs. 3. High myopia. The incidence of open-angle glaucoma is higher in patients with high myopia, and the incidence of myopia is also higher in open-angle glaucoma. Myopic eyes are susceptible to increased intraocular pressure, and because of the shallow scleral depression, it is not easy to identify, and because of the low scleral hardness, the intraocular pressure value measured with an indentation tonometer is often low. 4. Diabetes. The incidence of glaucoma in diabetic patients is 12.6%, which is significantly higher than the normal population. 5, systemic vascular disease. Patients with hypotension, in particular, are prone to insufficient blood supply to the optic disc, increasing the risk of optic nerve damage.