There are two types of dihuang: raw dihuang and cooked dihuang. The efficacy of raw Dihuang in wine is to clear heat and cool blood (to relieve blood heat by clearing heat), nourish yin and generate body fluid, with the effect of relieving yin deficiency and fever, etc. The efficacy of ripened Dihuang in wine is to nourish yin and tonify blood (to nourish the blood in the body), benefit essence and fill in the marrow, with the effect of relieving blood deficiency and atrophy and yellowish disease. 1. Radix Rehmanniae Praeparata: This drug has the effects of clearing heat and cooling blood, nourishing yin and generating body fluid, and can be used clinically for the treatment of yin deficiency and fever, thirst, vomiting blood, epistaxis, haematochezia, menstrual disorders, fetal restlessness, and constipation due to yin injury. When using this medicine, it should be noted that it is contraindicated for people with dampness in the spleen and stomach, Yang deficiency and phlegm in the chest and diaphragm. 2. Radix Rehmanniae Praeparata: This drug has the effect of tonifying blood and nourishing yin, benefiting essence and filling in the marrow. It can be clinically used in the treatment of blood deficiency and atrophy, palpitation and palpitations (violent heartbeat and panic), menstrual disorders, bleeding with disintegration, yin deficiency of liver and kidney (insufficient yin in the liver and kidneys), lumbar and knee soreness and tenderness (feeling of soreness and tenderness of waist and knees), tinnitus and premature graying of the beard and hair, and other diseases. While taking Radix Rehmanniae Praeparata, it is advisable to eat a light diet and avoid spicy and stimulating foods. In addition, when using raw Dihuang and cooked Dihuang to make wine, it should be noted that the efficacy of making wine is limited, and should not be used as a substitute for medication to treat diseases. If necessary, it is recommended to go to a regular hospital, under the guidance of a professional physician to identify the treatment.