The colloidal gold test for HIV antibodies is highly accurate, exceeding 90%. Colloidal gold is a highly accurate technique for the rapid detection of HIV antibodies in plasma or serum samples to assess HIV infection. The test is usually performed 14 to 21 days after adverse sexual contact and, if infected, will detect a positive result with an accuracy of more than 90%. Currently, there are many means of testing for HIV, including colloidal gold and chemiluminescence, each of which can be used to make a diagnosis. The window period for the test is about 2 to 6 weeks, generally after 6 weeks the test is negative, the probability of HIV infection can be excluded, but the follow-up still need to be monitored dynamically. Clinical testing for the presence of HIV antibodies is recommended at the Center for Disease Control and Prevention (CDC) or in the dermatology department of a hospital.