Most patients with hypertension need to take antihypertensive drugs for life, and therefore the adverse effects of antihypertensive drugs are of great importance to patients. Various antihypertensive drugs have different indications and adverse reactions, because each patient has individual differences, so the performance of adverse reactions also varies. Now several commonly used antihypertensive drugs adverse reactions are listed below for your reference: 1, diuretics: for early hypertension or mild hypertensive patients. Such as hydrochlorothiazide (dihydrochlorothiazide), chlorothiazide, furosemide (tachyphylaxis), etc., the main adverse reactions are hypokalemia, hypercalcemia, hyperglycemia and hyperlipidemia. In addition, it has adverse effects on patients with decompensated renal function and can cause an increase in blood urea nitrogen and creatinine. Therefore, it should be used with caution in patients with renal insufficiency. In addition, there is a diuretic antihypertensive drug called indapamide (Shoubishan), long-term use can cause hypokalemia, and occasionally can cause hyperuricemia, but no effect on blood calcium, blood sugar and blood lipids. Xuzhou Huancheng Community Health Service Center General Department of Tao Mingchun 2, β-blockers: for patients with mild to moderate hypertension with fast heart rate, good heart function with coronary angina. For example, propranolol (Jinan), metoprolol (Betaxolol), atenolol (amiloride) and bisoprolol (Bosu, Conco) can cause bradycardia, induce bronchial asthma, hyperglycemia, hyperlipidemia, etc.. They can also mask the clinical signs of hypoglycemia. If used in large doses, it can also induce acute heart failure. Therefore, it is not recommended for patients with combined atrioventricular block, hyperlipidemia, hyperuricemia, diabetes mellitus or asthma. 3, alpha-blockers: For patients with hypertension with obesity, hyperlipidemia and renal dysfunction. Commonly used are prazosin (pulse nimbin), terazosin (Gottlieb) and doxazosin (quinazosin). The latter two are also used to treat prostatic hyperplasia. A common adverse reaction is postural hypotension, especially when the first dose is taken, so the first dose should be taken in half before bedtime and care should be taken to avoid getting up at night as much as possible. 4, calcium antagonists: for patients with hypertension combined with renal insufficiency or diabetes. Such as dihydropyridine calcium antagonists commonly used in the controlled-release nifedipine tablets (Bison), felodipine (Boydin) and amlodipine (Loxodipine) can produce facial flushing, headache, rapid heartbeat, ankle edema and other side effects. Among them, nifedipine (cardiac pain) may occasionally cause hyperglycemia, therefore, it should not be used in combination with diabetes, and if it is necessary, it is generally recommended to use a small dose, and blood sugar should be reviewed regularly. Among the non-dihydropyridine calcium antagonists, verapamil (ipratropium) and diltiazem (pentoxifylline) may cause sinus bradycardia and atrioventricular block due to their inhibitory effects on sinus node function and atrioventricular conduction. Therefore, they should not be used in patients with bradycardia and atrioventricular block. However, the latter two do not have the side effect of ankle edema. In addition, Tenel Heart can occasionally cause malformation or stillbirth, so it is contraindicated in pregnant women. 5.Angiotensin-converting enzyme inhibitors: Suitable for patients with combined diabetes mellitus or mild renal decompensation, such as captopril (Kepoton), enalapril (Enyalin), benazepril (Lortin), cilazepril (Yipinsu), perindopril (Yashida) and fosinopril (Monox). The most common adverse reactions are different degrees of cough, mainly itchy throat and dry cough, with an incidence of 10%-20%. Other rare adverse reactions include angioneurotic edema, hyperkalemia, leukopenia, hypoglycemia, etc. Use with caution or not for patients with severe renal hypoplasia. 6, angiotensin II receptor antagonists: for hypertensive patients who cannot tolerate angiotensin-converting enzyme inhibitors. Such as Coxsartan (Coxua), Valsartan (Devon), etc.. No significant adverse reactions have been found, there can be mild dizziness, nausea, etc. Occasionally can cause hyperkalemia. 7, central antihypertensive drugs: for patients with hyperalgesia, renal hypertension or hypertension during pregnancy, such as methyldopa, colistin, etc. are caused by vertigo, postural hypotension and hypogonadism. 8, compound antihypertensive preparations: such as the commonly used compound antihypertensive tablets (compound descending tablets), Beijing antihypertensive 0, containing reserpine can cause drowsiness, weakness, nasal congestion, gastric bleeding, sexual dysfunction and other adverse reactions, ulcer disease patients use with caution. In addition, regular medicine antihypertensive tablets and Zhenju antihypertensive tablets can occasionally cause sexual dysfunction when taken for a long time, so middle-aged people should be used with caution. Compound Robitussin Tablets contain guanethidine, which may occasionally lead to upright hypotension and fall, so it should be used with caution by the elderly. Compound Captopril contains Captopril and hydrochlorothiazide, which may cause irritating dry cough and polyuria. Use with caution if you have chronic bronchitis and pharyngitis.