How long does it take for renal failure to occur in patients with chronic proteinuria is related to the amount of urine protein. If the amount of urine protein is particularly high, exceeding 350mg/24h, renal failure will usually occur in 3 to 5 years. If the 24-hour urine protein quantification is less than 1g, renal failure will generally occur after 10 years. The exact time cannot be generalised and is related to a variety of factors such as the individual patient’s physical condition and prognosis for treatment.